Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis

G. Hughes, Christopher; Mailloux, Patrick; W. Devlin, John; T. Swan, Joshua; D. Sanders, Robert; Anzueto, Antonio; C. Jackson, James; S. Hoskins, Aimee; T. Pun, Brenda; M Orun, Onur; Chandrasekhar, Rameela; L. Stollings, Joanna; L. Kiehl, Amy; S. Duprey, Matthew; N. Bui, Lan; R. O’Neal, Hollis; Snyder, Allison; A. Gropper, Michael; K. Guntupalli, Kalpalatha; J. Stashenko, Gregg; B. Patel, Mayur; E. Brummel, Nathan; D. Girard, Timothy; S. Dittus, Robert; R. Bernard, Gordon; Wesley Ely, E.; P. Pandharipande, Pratik

doi:10.1056/nejmoa2024922

Public

Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis

Published in New England Journal of Medicine • Feb 2, 2021

Authors:

Christopher G. Hughes

Patrick Mailloux

John W. Devlin

Abstract

BACKGROUND: Guidelines currently recommend targeting light sedation with dexmedetomidine or propofol for adults receiving mechanical ventilation. Differences exist between these sedatives in arousability, immunity, and inflammation. Whether they affect outcomes differentially in mechanically ventila...

Subject

Dexmedetomidine

Propofol

Sedation

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!