Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

Hou, Junyu; Lei, Zhimin; Cui, Linlu; Hou, Yun; Long, Yang; An, Ru; Wang, Qimeng; Li, Shengda; Zhang, Hongqin; Zhang, Lianshuang

doi:10.1016/j.ecoenv.2021.112012

Public

Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats

Published in Ecotoxicology and Environmental Safety • Feb 5, 2021

Authors:

Junyu Hou

Zhimin Lei

Linlu Cui

Abstract

Microplastics (MPs) considered as a new persistent environmental pollutant could enter into the circulatory system and result in decrease of sperm quantity and quality in mice. However, the effects of Polystyrene MPs (PS MPs) on the ovary and its mechanism in rats remained unclear. In this present s...

Subject

Apoptosis

Superoxide dismutase

Andrology

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