Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history

Coscollá, Mireia; Gagneux, Sébastien; Menardo, Fabrizio; Loiseau, Chloé; Ruiz-Rodríguez, Paula; Borrell, Sònia; Darko Otchere, Isaac; Asante-Poku, Adwoa; Asare, Prince; Sánchez-Busó, Leonor; Gehre, Florian; N’Dira Sanoussi, C.; Antonio, Martín; Affolabi, Dissou; Fyfe, Janet; Beckert, Patrick; Niemann, Stefan; Alabi, Abraham; P. Grobusch, Martin; Kobbe, Robin; Parkhill, Julian; Beisel, Christian; Fenner, Lukas; C. Böttger, Erik; J. Meehan, Conor; R. Harris, Simon; C. de Jong, Bouke; Yeboah‐Manu, Dorothy; Brites, Daniela

doi:10.1099/mgen.0.000477

Public

Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history

Published in Microbial Genomics • Feb 1, 2021

Authors:

Mireia Coscollá

Sébastien Gagneux

Fabrizio Menardo

Abstract

Human tuberculosis (TB) is caused by members of the Mycobacterium tuberculosis complex (MTBC). The MTBC comprises several human-adapted lineages known as M. tuberculosis sensu stricto , as well as two lineages (L5 and L6) traditionally referred to as Mycobacterium africanum . Strains of L5 and L6 ar...

Subject

Phylogenomics

Lineage (genetic)

Evolutionary biology

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