Primary Tumor Resection Plus Chemotherapy Versus Chemotherapy Alone for Colorectal Cancer Patients With Asymptomatic, Synchronous Unresectable Metastases (JCOG1007; iPACS): A Randomized Clinical Trial

Kanemitsu, Yukihide; Shitara, Kohei; Mizusawa, Junki; Hamaguchi, Tetsuya; Shida, Dai; Komori, Koji; Ikeda, Satoshi; Ojima, Hitoshi; Ike, Hideyuki; Shiomi, Akio; Watanabe, Jun; Takii, Yasumasa; Yamaguchi, Takashi; Katsumata, Kenji; Ito, Masaaki; Okuda, Junji; Hyakudomi, Ryoji; Shimada, Yasuhiro; Katayama, Hiroshi; Fukuda, Haruhiko; Colorectal Cancer Study Group, JCOG

doi:10.1200/jco.20.02447

Public

Primary Tumor Resection Plus Chemotherapy Versus Chemotherapy Alone for Colorectal Cancer Patients With Asymptomatic, Synchronous Unresectable Metastases (JCOG1007; iPACS): A Randomized Clinical Trial

Published in Journal of Clinical Oncology • Feb 9, 2021

Authors:

Yukihide Kanemitsu

Kohei Shitara

Junki Mizusawa

Abstract

PURPOSE It remains controversial whether primary tumor resection (PTR) before chemotherapy improves survival in patients with colorectal cancer (CRC) with asymptomatic primary tumor and synchronous unresectable metastases. PATIENTS AND METHODS This randomized phase III study investigated the superio...

Subject

Medicine

Chemotherapy

Asymptomatic

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