Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2

Gasser, Romain; Cloutier, Marc; Prévost, Jérémie; Fink, Corby; Ducas, Éric; Ding, Shilei; Dussault, Nathalie; Landry, Patricia; Tremblay, Tony; Laforce‐Lavoie, Audrey; Lewin, Antoine; Beaudoin-Bussières, Guillaume; Laumaea, Annemarie; Medjahed, Halima; Larochelle, Catherine; Richard, Jonathan; A. Dekaban, Gregory; D. Dikeakos, Jimmy; Bazin, Renée; Finzi, Andrés

doi:10.1016/j.celrep.2021.108790

Public

Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2

Published in Cell Reports • Feb 10, 2021

Authors:

Romain Gasser

Marc Cloutier

Jérémie Prévost

Abstract

Characterization of the humoral response to SARS-CoV-2, the etiological agent of COVID-19, is essential to help control the infection. The neutralization activity of plasma from patients with COVID-19 decreases rapidly during the first weeks after recovery. However, the specific role of each immunog...

Subject

Antibody

Neutralization

Convalescent plasma

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