Ultrasensitive detection of programmed death-ligand 1 (PD-L1) in whole blood using dispersible electrodes

Moazzam, Parisa; Myekhlai, Munkhshur; Alinezhad, Ali; A. Alshawawreh, Fida’a; Bakthavathsalam, Padmavathy; R. Gonçales, Vinícius; D. Tilley, Richard; Justin Gooding, J.

doi:10.1039/d0cc08068c

Public

Ultrasensitive detection of programmed death-ligand 1 (PD-L1) in whole blood using dispersible electrodes

Published in Chemical Communications • Jan 1, 2021

Authors:

Parisa Moazzam

Munkhshur Myekhlai

Ali Alinezhad

Abstract

The direct quantification of programmed death-ligand 1 (PD-L1) as a biomarker for cancer diagnosis, prognosis and treatment efficacy is an unmet clinical need. Herein, we demonstrate the first report of rapid, ultrasensitive and selective electrochemical detection of PD-L1 directly in undiluted whol...

Subject

Electrode

Ligand (biochemistry)

Electrochemistry

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