Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity

A. Wadden, Thomas; S. Bailey, Timothy; K. Billings, Liana; J. Davies, Melanie; P. Frías, Juan; Koroleva, Anna; Lingvay, Ildiko; M. O’Neil, Patrick; Rubino, Domenica; Skovgaard, Dorthe; Olrik Rytter Wallenstein, Signe; Timothy Garvey, W.; 3 Investigators, STEP

doi:10.1001/jama.2021.1831

Public

Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity

Published in JAMA • Feb 24, 2021

Authors:

Thomas A. Wadden

Timothy S. Bailey

Liana K. Billings

Abstract

Importance: Weight loss improves cardiometabolic risk factors in people with overweight or obesity. Intensive lifestyle intervention and pharmacotherapy are the most effective noninvasive weight loss approaches. Objective: To compare the effects of once-weekly subcutaneous semaglutide, 2.4 mg vs pla...

Subject

Medicine

Overweight

Body mass index

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