The role of m6A modification in the biological functions and diseases

Jiang, Xiulin; Liu, Baiyang; Nie, Zhi; Duan, Lincan; Xiong, Qiuxia; Jin, Zhixian; Yang, Cuiping; Chen, Yongbin

doi:10.1038/s41392-020-00450-x

Public

The role of m6A modification in the biological functions and diseases

Published in Signal Transduction and Targeted Therapy • Feb 21, 2021

Authors:

Xiulin Jiang

Baiyang Liu

Zhi Nie

Abstract

-methyladenosine (m6A) is the most prevalent, abundant and conserved internal cotranscriptional modification in eukaryotic RNAs, especially within higher eukaryotic cells. m6A modification is modified by the m6A methyltransferases, or writers, such as METTL3/14/16, RBM15/15B, ZC3H3, VIRMA, CBLL1, WT...

Subject

RNA methylation

Biology

N6-Methyladenosine

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