Prognostic significance of concurrent gene mutations in intensively treated patients with<i>IDH</i>-mutated AML: an ALFA study

Duchmann, Matthieu; Micol, Jean-Baptiste; Duployez, Nicolas; Raffoux, Emmanuel; Thomas, Xavier; Marolleau, Jean-Pierre; Braun, Thorsten; Adès, Lionel; Chantepie, Sylvain; Lemasle, Emilie; Berthon, Céline; Malfuson, Jean-Valère; Pautas, Cécile; Lambert, Juliette; Boissel, Nicolas; Celli-Lebras, Karine; Caillot, Denis; Turlure, Pascal; Vey, Norbert; Pigneux, Arnaud; Recher, Christian; Terré, Christine; Gardin, Claude; Itzykson, Raphaël; Preudhomme, Claude; Dombret, Hervé; de Botton, Stéphane

doi:10.1182/blood.2020010165

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Prognostic significance of concurrent gene mutations in intensively treated patients withIDH-mutated AML: an ALFA study

Shared by NobleBlocks on May 20, 2021 • 12:00 AM UTC

Authors:

Matthieu Duchmann

Jean-Baptiste Micol

Nicolas Duployez

Abstract

Abstract In patients with isocitrate dehydrogenase (IDH)–mutated acute myeloid leukemia (AML) treated by intensive chemotherapy (IC), prognostic significance of co-occurring genetic alterations and allogeneic hematopoietic stem cell transplantation (HSCT) are of particular interest with the advent o...

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