Euglycemic Diabetic Ketoacidosis and Sodium-Glucose Cotransporter-2 Inhibitors: A Focused Review of Pathophysiology, Risk Factors, and Triggers

Reddy Somagutta, Manoj; Agadi, Kuchalambal; Hange, Namrata; S Jain, Molly; Batti, Erkan; O Emuze, Bernard; O Amos-Arowoshegbe, Elizabeth; S Popescu, S; Hanan, Saad; Retna Kumar, Varadha; Pormento, Kezia

doi:10.7759/cureus.13665

Public

Euglycemic Diabetic Ketoacidosis and Sodium-Glucose Cotransporter-2 Inhibitors: A Focused Review of Pathophysiology, Risk Factors, and Triggers

Published in Cureus • Mar 3, 2021

Authors:

Manoj Reddy Somagutta

Kuchalambal Agadi

Namrata Hange

Abstract

Diabetic ketoacidosis (DKA) is an acute and significant life-threatening complication of diabetes. The association of sodium-glucose cotransporter-2 inhibitors (SGLT2i) with euglycemic diabetic ketoacidosis (EDKA) has been well reported. This literature review was conducted to understand the mechani...

Subject

Medicine

Diabetic ketoacidosis

Internal medicine

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