High Genetic Addiction Risk Score (GARS) in Chronically Prescribed Severe Chronic Opioid Probands Attending Multi-pain Clinics: an Open Clinical Pilot Trial

Moran, Mark; Blum, Kenneth; V. Ponce, Jessica; Lott, Lisa; C. Gondré‐Lewis, Marjorie; Badgaiyan, Sampada; Brewer, Raymond; W. Downs, Bernard; Fynman, Philip; Weingarten, Alexander; Lud Cadet, Jean; E. Smith, David; Baron, David; K. Thanos, Panayotis; J. Modestino, Edward; D. Badgaiyan, Rajendra; Elman, Igor; S. Gold, Mark

doi:10.1007/s12035-021-02312-1

Public

High Genetic Addiction Risk Score (GARS) in Chronically Prescribed Severe Chronic Opioid Probands Attending Multi-pain Clinics: an Open Clinical Pilot Trial

Published in Molecular Neurobiology • Mar 8, 2021

Authors:

Mark Moran

Kenneth Blum

Jessica V. Ponce

Abstract

Millions of Americans experience pain daily. In 2017, opioid overdose claimed 64,000 lives increasing to 84,000 lives in 2020, resulting in a decrease in national life expectancy. Chronic opioid use results in dependency, drug tolerance, neuroadaptation, hyperalgesia, potential addictive behaviors, ...

Subject

Medicine

Chronic pain

Opioid

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