Efficacy and safety of treatment with biologicals for severe chronic rhinosinusitis with nasal polyps: A systematic review for the EAACI guidelines

Agache, Ioana; Song, Yang; Alonso‐Coello, Pablo; Vogel, Yasmin; Rocha, Claudio; Solà, Iván; Santero, Marilina; A. Akdiş, Cezmi; Akdiş, Mübeccel; Walter Canonica, Giorgio; Chivato, Tomás; Del Giacco, Stefano; Eiwegger, Thomas; J. Fokkens, Wytske; Georgalas, Christos; Gevaert, Philippe; Hopkins, Claire; Klimek, Ludger; Lund, Valerie; M. Naclerio, Robert; O’Mahony, Liam; Palkonen, Susanna; Pfaar, Oliver; Schwarze, Jürgen; Soyka, Michael; Yun Wang, De; Zhang, Luo; Canelo‐Aybar, Carlos; Palomares, Óscar; Jutel, Marek

doi:10.1111/all.14809

Public

Efficacy and safety of treatment with biologicals for severe chronic rhinosinusitis with nasal polyps: A systematic review for the EAACI guidelines

Published in Allergy • Mar 8, 2021

Authors:

Ioana Agache

Yang Song

Pablo Alonso‐Coello

Abstract

This systematic review evaluates the efficacy and safety of biologicals for chronic rhinosinusitis with nasal polyps (CRSwNP) compared with the standard of care. PubMed, Embase, and Cochrane Library were searched for RCTs. Critical and important CRSwNP-related outcomes were considered. The risk of b...

Subject

Medicine

Nasal polyps

Mepolizumab

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