Immunoinformatics Design of Multi-Epitope Peptide-Based Vaccine Against Schistosoma mansoni Using Transmembrane Proteins as a Target

C. O. Sanches, Rodrigo; Tiwari, Sandeep; Cunha Grossi Ferreira, Laís; Martins de Oliveira, Flávio; D. Lopes, Marcelo; J. F. Passos, Maria; Habib Bechelane Maia, Eduardo; Gutterres Taranto, Alex; Bentes Kato, Rodrigo; Azevedo, Vasco; de Oliveira Lopes, Débora

doi:10.3389/fimmu.2021.621706

Public

Immunoinformatics Design of Multi-Epitope Peptide-Based Vaccine Against Schistosoma mansoni Using Transmembrane Proteins as a Target

Published in Frontiers in Immunology • Mar 2, 2021

Authors:

Rodrigo C. O. Sanches

Sandeep Tiwari

Laís Cunha Grossi Ferreira

Abstract

Schistosomiasis remains a serious health issue nowadays for an estimated one billion people in 79 countries around the world. Great efforts have been made to identify good vaccine candidates during the last decades, but only three molecules reached clinical trials so far. The reverse vaccinology app...

Subject

Epitope

Reverse vaccinology

Biology

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