Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit

Investigators, INSPIRATION; Mazloomzadeh, Saeideh; Khaleghparast, Shiva; Ghadrdoost, Behshid; Mousavizadeh, Mostafa; Reza Baay, Mohammad; Noohi, Feridoun; Sharifnia, Hamidreza; Ahmadi, Arezoo; Tavan, Sasan; Malekpour Alamdari, Nasser; Fathi, Mohammad; Soleimanzadeh, Mahshid; Mostafa, Mostafa; Davoody, Navid; Zarinsadaf, Maryam; Tayyebi, Sara; Farrokhzadeh, Fahimeh; Nezamabadi, Faeze; Soomari, Esmaeil; Sadeghipour, Parham; H. Talasaz, Azita; Rashidi, Farid; Sharif-Kashani, Babak; Taghi Beigmohammadi, Mohammad; Farrokhpour, Mohsen; Hashem Sezavar, Seyed; Payandemehr, Pooya; Dabbagh, Ali; Gohari Moghadam, Keivan; Jamalkhani, Sepehr; Khalili, Hossein; Yadollahzadeh, Mahdi; Riahi, Taghi; Rezaeifar, Parisa; Tahamtan, Ouria; Matin, Samira; Abedini, Atefeh; Lookzadeh, Somayeh; Rahmani, Hamid; Zoghi, Elnaz; Mohammadi, Keyhan; Sadeghipour, Pardis; Abri, Homa; Hariri Tabrizi, Sanaz; Masoud Mousavian, Seyed; Shahmirzaei, Shaghayegh; Bakhshandeh, Hooman; Amin, Ahmad; Rafiee, Farnaz; Baghizadeh, Elahe; Mohebbi, Bahram; Ehsan Parhizgar, Seyed; Aliannejad, Rasoul; Eslami, Vahid; Kashefizadeh, Alireza; Kakavand, Hessam; Hossein Hosseini, Seyed; Shafaghi, Shadi; Fattah Ghazi, Samrand; Najafi, Atabak; Jiménez, David; Gupta, Aakriti; V. Madhavan, Mahesh; S. Sethi, Sanjum; A. Parikh, Sahil; Monréal, Manuel; Hadavand, Naser; Hajighasemi, Alireza; Maleki, Majid; Sadeghian, Saeed; Piazza, Gregory; J. Kirtane, Ajay; Van Tassell, Benjamín; P. Dobesh, Paul; W. Stone, Gregg; Y.H. Lip, Gregory; M. Krumholz, Harlan; Z. Goldhaber, Samuel; Bikdeli, Behnood

doi:10.1001/jama.2021.4152

Public

Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit

Published in JAMA • Mar 18, 2021

Authors:

INSPIRATION Investigators

Saeideh Mazloomzadeh

Shiva Khaleghparast

Abstract

Importance: Thrombotic events are commonly reported in critically ill patients with COVID-19. Limited data exist to guide the intensity of antithrombotic prophylaxis. Objective: To evaluate the effects of intermediate-dose vs standard-dose prophylactic anticoagulation among patients with COVID-19 ad...

Subject

Medicine

Extracorporeal membrane oxygenation

Intensive care unit

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