Effect of Helmet Noninvasive Ventilation vs High-Flow Nasal Oxygen on Days Free of Respiratory Support in Patients With COVID-19 and Moderate to Severe Hypoxemic Respiratory Failure

Luca Grieco, Domenico; S. Menga, Luca; Cesarano, Melania; Rosà, Tommaso; Spadaro, Savino; Maddalena Bitondo, Maria; Montomoli, Jonathan; Falò, Giulia; Tonetti, Tommaso; Lucio Cutuli, Salvatore; Pintaudi, Gabriele; Sofia Tanzarella, Eloisa; Piervincenzi, Edoardo; Bongiovanni, Filippo; Maria Dell’Anna, Antonio; Delle Cese, Luca; Berardi, Cecilia; Carelli, Simone; Grazia Bocci, Maria; Montini, Luca; Bello, Giuseppe; Natalini, Daniele; De Pascale, Gennaro; Velardo, Matteo; Alberto Volta, Carlo; Marco Ranieri, V.; Conti, Giorgio; Maurizio Maggiore, Salvatore; Antonelli, Massimo; Gemelli Study Group, COVID-ICU; Marco Anzellotti, Gian; Cascarano, Laura; Ceccaroni, Francesca; De Santis, Paolo; Di Muro, Mariangela; Durante, Miriana; Filetici, Nicoletta; Gennenzi, Veronica; Gullì, Antonio; Lombardi, Gianmarco; Maccaglia, Alessio; Maviglia, Riccardo; Mele, Alessandro; Mercurio, Giovanna; Michi, Teresa; Christian Morena, Tony; Murdolo, Martina; Alberto Pennisi, Mariano; Postorino, Stefania; Potalivo, Antonella; Pozzana, Francesca; Rubino, Carlotta; Savino, Martina; Scarascia, Roberta; Scavone, Angela; Settanni, Donatella; Silva, Serena; Torrini, Flavia; Vargas, Joel; Zaccone, Carmelina

doi:10.1001/jama.2021.4682

Public

Effect of Helmet Noninvasive Ventilation vs High-Flow Nasal Oxygen on Days Free of Respiratory Support in Patients With COVID-19 and Moderate to Severe Hypoxemic Respiratory Failure

Published in JAMA • Mar 25, 2021

Authors:

Domenico Luca Grieco

Luca S. Menga

Melania Cesarano

Abstract

Importance: High-flow nasal oxygen is recommended as initial treatment for acute hypoxemic respiratory failure and is widely applied in patients with COVID-19. Objective: To assess whether helmet noninvasive ventilation can increase the days free of respiratory support in patients with COVID-19 comp...

Subject

Medicine

Fraction of inspired oxygen

Mechanical ventilation

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