Cells of the human intestinal tract mapped across space and time

Elmentaite, Rasa; Kumasaka, Natsuhiko; Roberts, Kenny; Fleming, Aaron; Dann, Emma; W. King, Hamish; Kleshchevnikov, Vitalii; Dabrowska, Monika; Pritchard, Sophie; Bolt, Liam; F. Vieira, Sara; Mamanova, Lira; Huang, Ni; Perrone, Francesca; Goh, Issac; Lisgo, Steven; Katan, Matilda; Leonard, Steven; R. W. Oliver, Thomas; Elizabeth Hook, C.; Nayak, Komal; S. Campos, Lia; Domínguez Conde, Cecilia; Stephenson, Emily; Engelbert, Justin; A. Botting, Rachel; Polański, Krzysztof; van Dongen, Stijn; Patel, Minal; D. Morgan, Michael; C. Marioni, John; Ali Bayraktar, Omer; B. Meyer, Kerstin; He, Xiaoling; A. Barker, Roger; H. Uhlig, Holm; T. Mahbubani, Krishnaa; Saeb‐Parsy, Kourosh; Zilbauer, Matthias; R. Clatworthy, Menna; Haniffa, Muzlifah; R. James, Kylie; A. Teichmann, Sarah

doi:10.1038/s41586-021-03852-1

Public

Cells of the human intestinal tract mapped across space and time

Published in Nature • Sep 8, 2021

Authors:

Rasa Elmentaite

Natsuhiko Kumasaka

Kenny Roberts

Abstract

The cellular landscape of the human intestinal tract is dynamic throughout life, developing in utero and changing in response to functional requirements and environmental exposures. Here, to comprehensively map cell lineages, we use single-cell RNA sequencing and antigen receptor analysis of almost ...

Subject

Biology

Immune system

Gastrointestinal tract

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