Neuroinflammatory Response to TNFα and IL1β Cytokines Is Accompanied by an Increase in Glycolysis in Human Astrocytes In Vitro

Pamies, David; Sartori, Chiara; Schvartz, Domitille; González‐Ruiz, Víctor; Pellerin, Luc; Nunes, Carolina; Tavel, Denise; Maillard, Vanille; Boccard, Julien; Rudaz, Serge; Sanchez, Jean‐Charles; Zurich, Marie‐Gabrielle

doi:10.3390/ijms22084065

Public

Neuroinflammatory Response to TNFα and IL1β Cytokines Is Accompanied by an Increase in Glycolysis in Human Astrocytes In Vitro

Published in International Journal of Molecular Sciences • Apr 14, 2021

Authors:

David Pamies

Chiara Sartori

Domitille Schvartz

Abstract

Astrogliosis has been abundantly studied in rodents but relatively poorly in human cells due to limited access to the brain. Astrocytes play important roles in cerebral energy metabolism, and are also key players in neuroinflammation. Astroglial metabolic and inflammatory changes as a function of ag...

Subject

Astrocyte

Astrogliosis

Biology

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