Metabolic Basis of Creatine in Health and Disease: A Bioinformatics-Assisted Review.

Diego A, Bonilla,; Richard B, Kreider,; Jeffrey R, Stout,; Diego A, Forero,; Chad M, Kerksick,; Michael D, Roberts,; Eric S, Rawson,

doi:10.3390/nu13041238

Public

Metabolic Basis of Creatine in Health and Disease: A Bioinformatics-Assisted Review.

Published in Nutrients • Apr 9, 2021

Authors:

Bonilla, Diego A

Kreider, Richard B

Stout, Jeffrey R

Abstract

Creatine (Cr) is a ubiquitous molecule that is synthesized mainly in the liver, kidneys, and pancreas. Most of the Cr pool is found in tissues with high-energy demands. Cr enters target cells through a specific symporter called Na+/Cl--dependent Cr transporter (CRT). Once within cells, creatine kina...

Subject

bioinformatics

cell survival

cellular allostasis

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