One-tube SARS-CoV-2 detection platform based on RT-RPA and CRISPR/Cas12a

Sun, Yangyang; Yu, Lei; Liu, Chengxi; Ye, Shanting; Chen, Wei; Li, Dechang; Huang, Weiren

doi:10.1186/s12967-021-02741-5

Public

One-tube SARS-CoV-2 detection platform based on RT-RPA and CRISPR/Cas12a

Published in Journal of Translational Medicine • Feb 16, 2021

Authors:

Yangyang Sun

Lei Yu

Chengxi Liu

Abstract

BACKGROUND: COVID-19 has spread rapidly around the world, affecting a large percentage of the population. When lifting certain mandatory measures for an economic restart, robust surveillance must be established and implemented, with nucleic acid detection for SARS-CoV-2 as an essential component. ME...

Subject

CRISPR

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Coronavirus disease 2019 (COVID-19)

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