COVID-19–related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters

Dias de Melo, Guilherme; Lazarini, Françoise; Levallois, Sylvain; Hautefort, Charlotte; Michel, Vincent; Larrous, Florence; Vérillaud, Benjamin; Aparicio, C.; Wagner, Sébastien; Gheusi, Gilles; Kergoat, Lauriane; Kornobis, Étienne; Donati, Flora; Cokelaer, Thomas; Hervochon, Rémi; Madec, Yoann; Roze, Emmanuel; Salmon, Dominique; Bourhy, Hervé; Lecuit, Marc; Lledo, Pierre‐Marie

doi:10.1126/scitranslmed.abf8396

Public

COVID-19–related anosmia is associated with viral persistence and inflammation in human olfactory epithelium and brain infection in hamsters

Shared by NobleBlocks on May 3, 2021 • 12:00 AM UTC

Authors:

Guilherme Dias de Melo

Françoise Lazarini

Sylvain Levallois

Abstract

Whereas recent investigations have revealed viral, inflammatory, and vascular factors involved in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung pathogenesis, the pathophysiology of neurological disorders in coronavirus disease 2019 (COVID-19) remains poorly understood. Olfactory ...

Subject

Anosmia

Olfactory epithelium

Persistence (discontinuity)

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