The network interplay of interferon and Toll-like receptor signaling pathways in the anti-Candida immune response

Coelho Salgado, Ranieri; Leandro M. Fonseca, Dennyson; H. C. Marques, Alexandre; Maria da Silva Napoleão, Sarah; Takahashi França, Tábata; Tiemi Akashi, Karen; Aliane de Souza Prado, Caroline; Baiocchi, G.; Rodrigues Plaça, Desirée; Jansen-Marques, Gabriel; Salerno Filgueiras, Igor; De Vito, Roberta; Paccielli Freire, Paula; Cabral de Miranda, Gustavo; Olsen Saraiva Câmara, Niels; Lúcia Garcia Calich, Vera; D. Ochs, Hans; F. Schimke, Lena; Jurišica, Igor; Condino‐Neto, Antônio; Cabral-Marques, Otávio

doi:10.1038/s41598-021-99838-0

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The network interplay of interferon and Toll-like receptor signaling pathways in the anti-Candida immune response

Published in Scientific Reports • Oct 13, 2021

Authors:

Ranieri Coelho Salgado

Dennyson Leandro M. Fonseca

Alexandre H. C. Marques

Abstract

Fungal infections represent a major global health problem affecting over a billion people that kills more than 1.5 million annually. In this study, we employed an integrative approach to reveal the landscape of the human immune responses to Candida spp. through meta-analysis of microarray, bulk, and...

Subject

Biology

Immune system

Transcriptome

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