Spermidine inhibits vascular calcification in chronic kidney disease through modulation of SIRT1 signaling pathway

Liu, Xiaoyu; Chen, An; Liang, Qingchun; Yang, Xiulin; Dong, Qianqian; Fu, Mingwei; Wang, Siyi; Li, Yining; Ye, Yuanzhi; Lan, Zirong; Chen, Yanting; Ou, Jing‐Song; Yang, Pingzhen; Lu, Lihe; Yan, Jianyun

doi:10.1111/acel.13377

Public

Spermidine inhibits vascular calcification in chronic kidney disease through modulation of SIRT1 signaling pathway

Published in Aging Cell • May 9, 2021

Authors:

Xiaoyu Liu

An Chen

Qingchun Liang

Abstract

Vascular calcification is a common pathologic condition in patients with chronic kidney disease (CKD) and aging individuals. It has been established that vascular calcification is a gene-regulated biological process resembling osteogenesis involving osteogenic differentiation. However, there is no e...

Subject

Spermidine

Calcification

Vascular smooth muscle

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