Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer

S Hall, Peter; Swinson, Daniel; A. Cairns, David; S. Waters, Justin; Petty, Russell; Allmark, Christine; Ruddock, Sharon; Falk, Stephen; Wadsley, Jonathan; Roy, Rajarshi; Tillett, Tania; J. Nicoll, J.; Cummins, Sebastian; Mano, Joseph; Grumett, Simon; Stokes, Zuzana; Kamposioras, Konstantinos-Velios; Chatterjee, Anirban; Garcia, Angel; Waddell, Tom; Guptal, Kamalnayan; Maisey, Nick; Q. Khan, Mohammed; Dent, Jo; Lord, Simon; Crossley, Ann; Katona, Eszter; Marshall, Helen; I. Grabsch, Heike; Velikova, Galina; Loo Ow, Pei; Handforth, Catherine; Howard, Helen; Seymour, Michel; Trial Investigators, GO2; James, Eleanor; Cheeseman, Sue; Roques, Tom; Reed, Nick; Candish, Charles; Fyfe, D.; Last, Kim; Ellis, Richard; Samuel, Lesley; Herbertson, Rebecca; Medley, Louise; Patel, Kinnari; Sherriff, David; Robinson, Angus; Bezecny, Pavel; Wilkins, Dunca; McGeoch, Adam; Propper, D.; Williams, Olwyn; Hilman, Serena; Raouf, Sherif; Hobbs, Claire; Parkinson, J.A.; Wadd, Nick; Saku, W; Kunene, Victori; Askill, C; Jamil, Arshad; Cattell, Emma; Gorf, Lauren; Vigneswaran, Vallipuram; Beaumont, Erica; M. Zubair, Syed; Jones, Elin; Reed, Nicholas; Shablak, Alaaeldin; Bozas, George; Rao, Sheela; Bennet, Michael; Askey, Joanne; Griffiths, Gareth; Clive, Sally; Potter, Vanessa; Roger Le Gall, Jean; Twelves, Chris; Sydes, M.R.; W. Valle, Juan; Webster, Jo; Jones, Marc; Collinson, Fiona; Brown, Julia; Brook, Louise

doi:10.1001/jamaoncol.2021.0848

Public

Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer

Published in JAMA Oncology • May 13, 2021

Authors:

Peter S Hall

Daniel Swinson

David A. Cairns

Abstract

Importance: Older and/or frail patients are underrepresented in landmark cancer trials. Tailored research is needed to address this evidence gap. Objective: The GO2 randomized clinical trial sought to optimize chemotherapy dosing in older and/or frail patients with advanced gastroesophageal cancer, ...

Subject

Medicine

Capecitabine

Oxaliplatin

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!