Lifileucel, a Tumor-Infiltrating Lymphocyte Therapy, in Metastatic Melanoma

A. Sarnaik, Amod; Hamid, Omid; I. Khushalani, Nikhil; D. Lewis, Karl; Medina, Theresa; M. Kluger, Harriet; Thomas, Sajeve; Domingo‐Musibay, Evidio; C. Pavlick, Anna; D. Whitman, Eric; Martín‐Algarra, Salvador; Corrie, Pippa; D. Curti, Brendan; Oláh, Judit; Lutzky, Jose; S. Weber, Jeffrey; Larkin, James; Shi, Wen; Takamura, Toshimi; Jagasia, Madan; Qin, Harry; Wu, Xiao; Chartier, Cécile; Graf Finckenstein, Friedrich; Fardis, Maria; M. Kirkwood, John; Chesney, Jason

doi:10.1200/jco.21.00612

Public

Lifileucel, a Tumor-Infiltrating Lymphocyte Therapy, in Metastatic Melanoma

Published in Journal of Clinical Oncology • May 12, 2021

Authors:

Amod A. Sarnaik

Omid Hamid

Nikhil I. Khushalani

Abstract

PURPOSE: Effective treatment options are limited for patients with advanced (metastatic or unresectable) melanoma who progress after immune checkpoint inhibitors and targeted therapies. Adoptive cell therapy using tumor-infiltrating lymphocytes has demonstrated efficacy in advanced melanoma. Lifileu...

Subject

Medicine

Melanoma

Internal medicine

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