Double Trap Interface: A novel gas interface for high throughput analysis of biomedical samples by AMS

De Maria, Daniele; Fahrni, Simon; Lozac’h, Frédéric; Marvalin, Cyrille; Walles, Markus; Camenisch, Gian; Wacker, Lukas; Synal, Hans‐Arno

doi:10.1016/j.dmpk.2021.100400

Public

Double Trap Interface: A novel gas interface for high throughput analysis of biomedical samples by AMS

Published in Drug Metabolism and Pharmacokinetics • May 7, 2021

Authors:

Daniele De Maria

Simon Fahrni

Frédéric Lozac’h

Abstract

Although Accelerator Mass Spectrometry (AMS) offers unparalleled sensitivity by investigating the fate of 14C-labeled compounds within the organism, its widespread use in ADME (absorption, distribution, metabolism, excretion) studies is limited. Conventional approaches based on Liquid Scintillation ...

Subject

Accelerator mass spectrometry

Sample preparation

Chemistry

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