Exosomes derived from pioglitazone-pretreated MSCs accelerate diabetic wound healing through enhancing angiogenesis

Hu, Yiqiang; Tao, Ranyang; Chen, Lang; Xiong, Yuan; Xue, Hang; Hu, Liangcong; Yan, Chenchen; Xie, Xudong; Lin, Ze; C. Panayi, Adriana; Mi, Bobin; Liu, Guohui

doi:10.1186/s12951-021-00894-5

Public

Exosomes derived from pioglitazone-pretreated MSCs accelerate diabetic wound healing through enhancing angiogenesis

Published in Journal of Nanobiotechnology • May 21, 2021

Authors:

Yiqiang Hu

Ranyang Tao

Lang Chen

Abstract

BACKGROUND: Enhanced angiogenesis can promote diabetic wound healing. Mesenchymal stem cells (MSCs)-derived exosomes, which are cell-free therapeutics, are promising candidates for the treatment of diabetic wound healing. The present study aimed to investigate the effect of exosomes derived from MSC...

Subject

Angiogenesis

Wound healing

Pioglitazone

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