KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis

Bu, Dechao; Luo, Haitao; Huo, Peipei; Wang, Zhihao; Zhang, Shan; He, Zihao; Wu, Yang; Zhao, Lianhe; Liu, Jingjia; Guo, Jincheng; Fang, Shuangsang; Cao, Wanchen; Yi, Lan; Zhao, Yi; Kong, Lei

doi:10.1093/nar/gkab447

Public

KOBAS-i: intelligent prioritization and exploratory visualization of biological functions for gene enrichment analysis

Shared by NobleBlocks on Jun 4, 2021 • 12:00 AM UTC

Authors:

Dechao Bu

Haitao Luo

Peipei Huo

Abstract

Abstract Gene set enrichment (GSE) analysis plays an essential role in extracting biological insight from genome-scale experiments. ORA (overrepresentation analysis), FCS (functional class scoring), and PT (pathway topology) approaches are three generations of GSE methods along the timeline of devel...

Discussions