Effect of Continuous Infusion of Hypertonic Saline vs Standard Care on 6-Month Neurological Outcomes in Patients With Traumatic Brain Injury

Roquilly, Antoine; Moyer, Jean-Denis; Huet, Olivier; Lasocki, Sigismond; L. Cohen, Benjamin; Dahyot‐Fizelier, Claire; Chalard, Kévin; Séguin, Philippe; Jeantrelle, Caroline; Vermeersch, Véronique; Gaillard, Thomas; Cinotti, Raphaël; Demeure Dit Latte, Dominique; Mahé, Pierre; Vourc’h, Mickaël; Martin, Florian; Chopin, Alice; Lerebourg, Céline; Flet, Laurent; Chiffoleau, Anne; Feuillet, Fanny; Asehnoune, Karim; Beloeil, Hélène; Launey, Yoann; Tawa, Audrey; Bellier, Rémy; Bénard, Thierry; Gergaud, Soizic; Léger, Maxime; Perrigault, Pierre-Francois; Hego, Camille; Holleville, Mathilde; Yannick, Hourmant; Marwan, Bouras; Francis, R.J.; Alexandre, Bourdiol; Ichai, Carole; Stocchetti, Nino; Molinari, Nicolas

doi:10.1001/jama.2021.5561

Public

Effect of Continuous Infusion of Hypertonic Saline vs Standard Care on 6-Month Neurological Outcomes in Patients With Traumatic Brain Injury

Published in JAMA • May 25, 2021

Authors:

Antoine Roquilly

Jean-Denis Moyer

Olivier Huet

Abstract

Importance: Fluid therapy is an important component of care for patients with traumatic brain injury, but whether it modulates clinical outcomes remains unclear. Objective: To determine whether continuous infusion of hypertonic saline solution improves neurological outcome at 6 months in patients wi...

Subject

Medicine

Hypertonic saline

Traumatic brain injury

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