Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-B.1.1.7 or B.1.1.7 SARS-CoV-2 variants

Monel, Blandine; Planas, Delphine; Grzelak, Ludivine; Smith, Nikaïa; Robillard, Nicolas; Staropoli, Isabelle; Gonçalves, Pedro; Porrot, Françoise; Guivel‐Benhassine, Florence; Demory Guinet, Nathalie; Rodary, Julien; Puech, Julien; Euzen, Victor; Bélec, Laurent; Orvoën, Galdric; Nunes, Léa; Moulin, Véronique; Fourgeaud, Jacques; Wack, Maxime; Imbeaud, Sandrine; Campagne, Pascal; Duffy, Darragh; P. Di Santo, James; Bruel, Timothée; Péré, Hélène; Veyer, David; Schwartz, Olivier

doi:10.1101/2021.05.20.21257393

Public

Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-B.1.1.7 or B.1.1.7 SARS-CoV-2 variants

Published in medRxiv • May 22, 2021

Authors:

Blandine Monel

Delphine Planas

Ludivine Grzelak

Abstract

Abstract The mechanisms that allowed for the SARS-CoV-2 B.1.1.7 variant to rapidly outcompete pre-existing variants in many countries remain poorly characterized. Here, we analyzed viral release, anti-SARS-CoV-2 antibodies and cytokine production in a retrospective series of 427 RT–qPCR+ nasopharyng...

Subject

Virology

Virus

Titer

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