A phase 2 trial of inhaled nitrous oxide for treatment-resistant major depression

Nagele, Peter; J. Palanca, Ben; Gott, Britt; Brown, Frank; Barnes, Linda; Nguyen, Thomas; Xiong, Willa; C. Salloum, Naji; D. Espejo, Gemma; N. Lessov-Schlaggar, Christina; Jain, Nisha; W. L. Cheng, Wayland; Komen, Helga; Yee, Branden; D. Bolzenius, Jacob; Janski, Alvin; Gibbons, Robert; F. Zorumski, Charles; R. Conway, Charles

doi:10.1126/scitranslmed.abe1376

Public

A phase 2 trial of inhaled nitrous oxide for treatment-resistant major depression

Shared by NobleBlocks on Jun 9, 2021 • 12:00 AM UTC

Authors:

Peter Nagele

Ben J. Palanca

Britt Gott

Abstract

Twenty-five percent inhaled nitrous oxide improves symptoms of treatment-resistant major depression with fewer adverse effects than the 50% concentration.

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