Hypoxia-Inducible Exosomes Facilitate Liver-Tropic Premetastatic Niche in Colorectal Cancer.

H, Sun; Q, Meng; C, Shi; H, Yang; X, Li; S, Wu; G, Familiari; M, Relucenti; M, Aschner; X, Wang; R, Chen

doi:10.1002/hep.32009

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Hypoxia-Inducible Exosomes Facilitate Liver-Tropic Premetastatic Niche in Colorectal Cancer.

Shared by NobleBlocks on Sep 9, 2021 • 12:00 AM UTC

Authors:

Sun H

Meng Q

Shi C

Abstract

Background and aims Liver metastasis is a frequent occurrence in patients with colorectal cancer (CRC), with 15%-25% of CRC patients having liver metastases at the time of initial diagnosis. Specifically, some regional-stage patients with mild symptoms (stage 1 or 2) will also advance to liver metas...

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