Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest

Dankiewicz, Josef; Cronberg, Tobias; Lilja, Gisela; Christian Jakobsen, Janus; Levin, Helena; Ullén, Susann; Rylander, Christian; P. Wise, Matt; Oddo, Mauro; Cariou, Alain; Bělohlávek, Jan; Hovdenes, Jan; Saxena, Manoj; Kirkegaard, Hans; J. Young, Paul; Pelosi, Paolo; Storm, Christian; Silvio Taccone, Fabio; Joannidis, Michael; W. Callaway, Clifton; M. Eastwood, Glenn; Morgan, Matt; Nordberg, Per; Erlinge, David; Nichol, Alistair; S. Chew, Michelle; Hollenberg, Jacob; Thomas, Matthew; Bewley, Jeremy; Sweet, Katie; Morten Grejs, Anders; Christensen, Steffen; Hænggi, Matthias; Levis, Anja; Lundin, Andreas; Düring, Joachim; Schmidbauer, Simon; Keeble, Thomas; V. Karamasis, Grigoris; Schrag, Claudia; Faessler, Edith; Šmíd, Ondřej; Otáhal, Michal; Maggiorini, Marco; David Wendel‐Garcia, Pedro; Jaubert, Paul; Cole, Jade; Solař, Miroslav; Borgquist, Ola; Leithner, Christoph; Abed‐Maillard, Samia; Navarra, Leanlove; Annborn, Martin; Undén, Johan; Brunetti, Iole; Awad, Akil; McGuigan, Peter; Bjørkholt Olsen, Roy; Cassina, Tiziano; Vignon, Philippe; Langeland, Halvor; Lange, Theis; Friberg, Hans; Nielsen, Niklas

doi:10.1056/nejmoa2100591

Public

Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest

Published in New England Journal of Medicine • Jun 16, 2021

Authors:

Josef Dankiewicz

Tobias Cronberg

Gisela Lilja

Abstract

BACKGROUND: Targeted temperature management is recommended for patients after cardiac arrest, but the supporting evidence is of low certainty. METHODS: In an open-label trial with blinded assessment of outcomes, we randomly assigned 1900 adults with coma who had had an out-of-hospital cardiac arrest...

Subject

Hypothermia

Medicine

Anesthesia

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