Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set

A. Klein, Eric; Richards, Donald; Lee Cohn, Allen; Tummala, Meghna; L. Lapham, Rosanna; O. Cosgrove, David; G. Chung, Gina; Clement, Jessica; Gao, Jingjing; Hunkapiller, Nathan; Jamshidi, Arash; N. Kurtzman, Kathryn; V. Seiden, Michael; Swanton, Charles; C Liu, M

doi:10.1016/j.annonc.2021.05.806

Public

Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set

Published in Annals of Oncology • Jun 24, 2021

Authors:

Eric A. Klein

Donald Richards

Allen Lee Cohn

Abstract

BACKGROUND: A multi-cancer early detection (MCED) test used to complement existing screening could increase the number of cancers detected through population screening, potentially improving clinical outcomes. The Circulating Cell-free Genome Atlas study (CCGA; NCT02889978) was a prospective, case-c...

Subject

Medicine

Cancer

Stage (stratigraphy)

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