Characteristics of Early-Onset vs Late-Onset Colorectal Cancer

Collaborative, REACCT; Zaborowski, Alexandra; Abdile, Ahmed; Adamina, Michel; Aigner, Felix; d’Allens, Laura; Allmer, Caterina; Álvarez, Andrea; Anula, Rocío; Andric, Mihailo; Atallah, S.; P. Bach, Simon; Bala, Miklosh; Barussaud, Marie; Baušys, Augustinas; Bebington, Brendan; D. Beggs, Andrew; Bellolio, Felipe; Bennett, Melissa-Rose; Berdinskikh, Anton; Bevan, Vicki; Biondo, Sebastiano; Bislenghi, Gabriele; Bludau, Marc; Boutall, Adam; P.M. Brouwer, Nelleke; J. Brown, Carl; J. Bruns, Christiane; D. Buchanan, Daniel; Buchwald, Pamela; W. A. Burger, Jacobus; Бурлов, Никита; Campanelli, Michela; Capdepont, Maylis; Carvello, Michele; Chew, Hwee-Hoon; Christoforidis, Dimitri; A. Clark, David; Climent, Marta; G. Cologne, Kyle; Contreras, Tomás; S. Croner, Roland; R. Daniels, I.; Dapri, Giovanni; Davies, Justin; Delrio, Paolo; Denost, Quentin; Deutsch, Michael; Roncon Dias, André; D’Hoore, André; S. Drozdov, E.; Duek, Daniel; G. Dunlop, Malcolm; Dziki, Adam; Edmundson, Aleksandra; Efetov, Sergey; El‐Hussuna, Alaa; Elliot, Brodie; Hany Emile, Sameh; Espín, Eloy; D. Evans, M.; Faes, Seraina; Faiz, Omar; J. Fleming, Fergal; Foppa, Caterina; Fowler, G; Frasson, Matteo; Figueiredo, Nuno; Forgan, Tim; Frizelle, Frank; Gadaev, Shamil; Gellona, José; Glyn, Tamara; Gong, Jianping; Barisic, Goran; Greenwood, Emma; G. Guren, Marianne; Guillon, Stephanie; Gutlic, Ida; Hahnloser, Dieter; Hampel, Heather; Hanly, Ann; Hasegawa, Hirotoshi; Hjerrild Iversen, Lene; Hill, Andrew; Hill, James; Hoch, Jiří; Hoffmeister, Michael; Hompes, Roel; Hurtado‐Pardo, Luis; Iaquinandi, Fabiano; Imbrasaitė, Ugnė; Islam, Rumana; Dorna Jafari, Mehrenah; Kanemitsu, Yukihide; М. Карачун, А.; Karimuddin, Ahmer; S. Keller, Deborah; Kelly, Justin; Kennelly, Rory; Khrykov, Gleb; Kocián, Petr; Koh, Cherry; F. M. Kok, N.; Knight, Katrina; Knol, Joep; Kontovounisios, Christos; Kørner, Hartwig; Krivokapić, Zoran; Kronberger, Irmgard; M. Kroon, Hidde; Kryžauskas, Marius; Kural, Said; Kusters, Miranda; Lakkis, Zaher; Lankov, Timur; Larson, Dave; Lázár, György; Lee, Kai-Yin; Lee, Suk-Hwan; H. Lefèvre, Jérémie; Lepistö, Anna; H. Lieu, Christopher; Loi, Lynette; Lynch, Craig; Maillou‐Martinaud, Helene; Maroli, Annalisa; Martin, Sean; Martling, Anna; E. Matzel, Klaus; Mayol, Julio; McDermott, Frank; Meurette, G.; Millán, Mónica; Mitteregger, Martin; С Моисеенко, А; R.T. Monson, John; Morărașu, Ștefan; Moritani, Konosuke; Möslein, Gabriela; Munini, Martino; Sérgio Rizkallah Nahas, Caio; Carlos Nahas, Sérgio; Negoi, Ionuţ; Novikova, A; Ocares, Misael; Okabayashi, Koji; Olkina, Alexandra; F. Oñate‐Ocaña, Luis; Otero, Jaime; Özen, Cihan; Pace, Ugo; Pagin São Julião, Guilherme; Panaiotti, Lidiia; Panís, Yves; Papamichael, Demetris; Park, Jason; Patel, Swati; C Patrón Uriburu, Juan; Pera, Miguél; Oliva Perez, Rodrigo; Н. Петров, А.; Pfeffer, F.; Terry Phang, P.; Poškus, Tomas; Pringle, Heather; Proud, David; Raguz, Ivana; Rama, N.; Rasheed, Shahnawaz; J. Raval, Manoj; Rega, Daniela; Reißfelder, Christoph; Carlos Reyes Meneses, Juan; Ris, Frédéric; Riss, Stefan; Rodríguez‐Zentner, Homero; S.D. Roxburgh, Campbell; Saklani, Avanish; Jiménez Salido, Andrea; Sammour, Tarik; Saraste, Deborah; Schneider, Martin; Seishima, Ryo; Sekulic, Aleksander; T. Seppälä, Toni; Sheahan, Kieran; Shine, Rebecca; Shlomina, Alexandra; S. Sica, Guiseppe; Singnomklao, T; Siragusa, Leandro; Smart, Neil; Solís, Alejandro; Spinelli, Antonino; D. Staiger, Roxane; J. Stamos, Michael; R. Steele, Scott; Sunderland, Michael; Tan, Ker‐Kan; J. Tanis, Pieter; Tekkis, Paris; Teklay, Biniam; Tengku, Sabrina; Jiménez‐Toscano, Marta; Tsarkov, Petr; Turina, Matthias; Ulrich, Alexis; Borba Vailati, Bruna; van Harten, Meike; Verhoef, Cornelis; K. Warrier, Satish; Wexner, Steve; De Wilt, Hans; A. Weinberg, Benjamin; I. Wells, Cameron; Wolthuis, Albert; Xynos, Evangelos; You, Nancy; Zakharenko, Alexander; Zeballos, Justino; C. Winter, D.

doi:10.1001/jamasurg.2021.2380

Public

Characteristics of Early-Onset vs Late-Onset Colorectal Cancer

Published in JAMA Surgery • Jun 30, 2021

Authors:

REACCT Collaborative

Alexandra Zaborowski

Ahmed Abdile

Abstract

Importance: The incidence of early-onset colorectal cancer (younger than 50 years) is rising globally, the reasons for which are unclear. It appears to represent a unique disease process with different clinical, pathological, and molecular characteristics compared with late-onset colorectal cancer. ...

Subject

Medicine

Colorectal cancer

Internal medicine

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