Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress

Zhang, Qing; Liu, Jia; Duan, Huxinyue; Li, Ruolan; Peng, Wei; Wu, Chunjie

doi:10.1016/j.jare.2021.06.023

Public

Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress

Published in Journal of Advanced Research • Jul 6, 2021

Authors:

Qing Zhang

Jia Liu

Huxinyue Duan

Abstract

Introduction: Recently, Nrf2/HO-1 has received extensive attention as the main regulatory pathway of intracellular defense against oxidative stress and is considered an ideal target for alleviating endothelial cell (EC) injury. Objectives: This paper aimed to summarized the natural monomers/extracts...

Subject

Oxidative stress

Pharmacology

Apoptosis

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