YTHDF2 facilitates UBXN1 mRNA decay by recognizing METTL3-mediated m6A modification to activate NF-κB and promote the malignant progression of glioma

Abstract Background The prognosis for diffuse gliomas is very poor and the mechanism underlying their malignant progression remains unclear. Here, we aimed to elucidate the role and mechanism of the RNA N 6,2′- O -dimethyladenosine (m 6 A) reader, YTH N 6-methyladenosine RNA binding protein 2 (YTHDF... View More