TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer

Xu, Jiahui; Yang, Xiaoli; Deng, Qiaodan; Yang, Cong; Wang, Dong; Jiang, Guojuan; Yao, Xiaohong; He, Xueyan; Ding, Jiajun; Qiang, Jiankun; Tu, Juchuanli; Zhang, Rui; Lei, Qun‐Ying; Shao, Zhimin; Bian, Xiu‐Wu; Hu, Ronggui; Zhang, Lixing; Liu, Suling

doi:10.1038/s41467-021-24703-7

Public

TEM8 marks neovasculogenic tumor-initiating cells in triple-negative breast cancer

Published in Nature Communications • Jul 20, 2021

Authors:

Jiahui Xu

Xiaoli Yang

Qiaodan Deng

Abstract

Enhanced neovasculogenesis, especially vasculogenic mimicry (VM), contributes to the development of triple-negative breast cancer (TNBC). Breast tumor-initiating cells (BTICs) are involved in forming VM; however, the specific VM-forming BTIC population and the regulatory mechanisms remain undefined....

Subject

Triple-negative breast cancer

Cancer research

Population

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