CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome.

F, Taube; JA, Georgi; M, Kramer; S, Stasik; JM, Middeke; C, Röllig; U, Krug; A, Krämer; S, Scholl; A, Hochhaus; TH, Brümmendorf; R, Naumann; A, Petzold; R, Mulet-Lazaro; PJM, Valk; B, Steffen; H, Einsele; M, Schaich; A, Burchert; A, Neubauer; K, Schäfer-Eckart; C, Schliemann; SW, Krause; M, Hänel; R, Noppeney; U, Kaiser; CD, Baldus; M, Kaufmann; S, Herold; F, Stölzel; K, Sockel; Bonin M, von; C, Müller-Tidow; U, Platzbecker; WE, Berdel; H, Serve; G, Ehninger; M, Bornhäuser; J, Schetelig; C, Thiede

doi:10.1182/blood.2020009680

Public

CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome.

Shared by NobleBlocks on Jan 1, 2022 • 12:00 AM UTC

Authors:

Taube F

Georgi JA

Kramer M

Abstract

Biallelic mutations of the CEBPA gene (CEBPAbi) define a distinct entity associated with favorable prognosis; however, the role of monoallelic mutations (CEBPAsm) is poorly understood. We retrospectively analyzed 4708 adults with acute myeloid leukemia (AML) who had been recruited into the Study All...

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!