SARS-CoV-2 Poorly Replicates in Cells of the Human Blood-Brain Barrier Without Associated Deleterious Effects

Constant, Orianne; Barthelemy, Jonathan; Bolloré, Karine; Tuaillon, Édouard; Gosselet, Fabien; Chable-Bessia, Christine; Mérida, Peggy; Muriaux, Delphine; Van de Perre, Philippe; Salinas, Sara; Simonin, Yannick

doi:10.3389/fimmu.2021.697329

Public

SARS-CoV-2 Poorly Replicates in Cells of the Human Blood-Brain Barrier Without Associated Deleterious Effects

Published in Frontiers in Immunology • Jul 27, 2021

Authors:

Orianne Constant

Jonathan Barthelemy

Karine Bolloré

Abstract

Various neurological symptoms have been associated to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection including headache, fever, anosmia, ageusia, but also, encephalitis, Guillain-Barre syndrome and ischemic stroke. Responsible for the current coronavirus disease (COVID-19) pa...

Subject

Blood–brain barrier

Anosmia

Medicine

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