CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability

Zhang, Yu; Jiang, Jiajia; Zhang, Jiayin; Shen, Han; Wang, Maoye; Guo, Zhen; Zang, Xueyan; Shi, Hui; Gao, Jiayan; Cai, Hui; Fang, Xinjian; Qian, Hui; Xu, Wenrong; Zhang, Xu

doi:10.1186/s12943-021-01390-y

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CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability

Published in Molecular Cancer • Aug 12, 2021

Authors:

Yu Zhang

Jiajia Jiang

Jiayin Zhang

Abstract

BACKGROUND: Circular RNAs (circRNAs) play important roles in cancer development and progression. The purpose of this study is to identify aberrantly expressed circRNAs in gastric cancer (GC), unravel their roles in GC progression, and provide new targets for GC diagnosis and therapy. METHODS: Bioinf...

Subject

Biology

Protein stability

Cancer research

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