Safety and feasibility of research lumbar puncture in Huntington’s disease: the HDClarity cohort and bioresource

B. Rodrigues, Filipe; Owen, Gail; Sathe, Swati; S. Pak, Elena; Kaur, Dipinder; G Ehrhardt, Anka; Lifer, Sherry; Townhill, Jenny; Schubert, Katarzyna; R. Leavitt, Blair; Guttman, Mark; Bang, Jee; Lewerenz, Jan; Levey, Jamie; the HDClarity Investigators, for; Sampaio, Cristina; J. Wild, Edward

doi:10.1101/2021.07.30.21261340

Public

Safety and feasibility of research lumbar puncture in Huntington’s disease: the HDClarity cohort and bioresource

Shared by NobleBlocks on Jul 31, 2021 • 12:00 AM UTC

Authors:

Filipe B. Rodrigues

Gail Owen

Swati Sathe

Abstract

STRUCTURED ABSTRACT Background Biomarkers are needed to monitor disease progression, target engagement and efficacy in Huntington’s disease (HD). Cerebrospinal fluid (CSF) is an ideal medium to research such biomarkers due to its proximity to the brain. Objectives To investigate the safety and feasi...

Subject

Medicine

Headaches

Venipuncture

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!