The stability of the metabolic turnover of arachidonic acid in human unruptured intracranial aneurysmal walls is sustained

Takeda, Ririko; Islam, Ariful; Sato, Tomohito; Kurita, Hiroki; Kahyo, Tomoaki; Urano, Tetsumei; Setou, Mitsutoshi

doi:10.1016/j.clineuro.2021.106881

Public

The stability of the metabolic turnover of arachidonic acid in human unruptured intracranial aneurysmal walls is sustained

Published in Clinical Neurology and Neurosurgery • Aug 8, 2021

Authors:

Ririko Takeda

Ariful Islam

Tomohito Sato

Abstract

OBJECTIVE: Intracranial aneurysm (IA) is considered a chronic inflammatory condition that affects intracranial arteries. Cyclooxygenase 2 (COX2) and prostaglandin E2 (PGE2) are considered potential targets of specific medical treatment for IAs. Previous studies have reported the elevated COX2 expres...

Subject

Arachidonic acid

Medicine

Aneurysm

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