Geranyl-geraniol addition affects potency of bisphosphonates-a comparison in vitro promising a therapeutic approach for bisphosphonate-associated osteonecrosis of the jaw and oral wound healing.

M, Otto; C, Lux; T, Schlittenbauer; F, Halling; T, Ziebart

doi:10.1007/s10006-021-00982-8

Public

Geranyl-geraniol addition affects potency of bisphosphonates-a comparison in vitro promising a therapeutic approach for bisphosphonate-associated osteonecrosis of the jaw and oral wound healing.

Shared by NobleBlocks on Aug 15, 2021 • 12:00 AM UTC

Authors:

Otto M

Lux C

Schlittenbauer T

Abstract

Purpose Analysis of the influence of geranyl-geraniol (GG) addition on four bisphosphonate derivatives regarding their influence on cell viability and migration ability of bone metabolism and endothelial cells in vitro.Methods Clodronate, pamidronate, ibandronate, and zoledronate were observed with ...

Subject

Cell viability

Bisphosphonate-associated Osteonecrosis Of The Jaw

Migration Ability

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