Effect of Colchicine on Myocardial Injury in Acute Myocardial Infarction

Mewton, Nathan; Roubille, François; Bresson, Didier; Prieur, Cyril; Bouleti, Claire; Bochaton, Thomas; Ivanés, Fabrice; Dubreuil, Olivier; Bière, Loïc; Hayek, Ahmad; Dérimay, François; Akodad, Mariama; Alos, Benjamin; Haider, Lamis; El Jonhy, Naoual; H. Daw, R.; de Bourguignon, Charles; Dhelens, C.; Finet, Gérard; Bonnefoy‐Cudraz, Eric; Bidaux, Gabriel; Boutitie, Florent; Maucort‐Boulch, Delphine; Croisille, Pierre; Rioufol, Gilles; Prunier, Fabrice; Angoulvant, Denis; behalf of the COVERT-MI Study Investigators, on

doi:10.1161/circulationaha.121.056177

Public

Effect of Colchicine on Myocardial Injury in Acute Myocardial Infarction

Published in Circulation • Aug 23, 2021

Authors:

Nathan Mewton

François Roubille

Didier Bresson

Abstract

Background: Inflammation is a key factor of myocardial damage in reperfused ST-segment–elevation myocardial infarction. We hypothesized that colchicine, a potent anti-inflammatory agent, may reduce infarct size (IS) and left ventricular (LV) remodeling at the acute phase of ST-segment–elevation myoc...

Subject

Medicine

Myocardial infarction

Internal medicine

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