Chromatin and transcription factor profiling in rare stem cell populations using CUT&amp;Tag

Li, Yuefeng; Nakka, Kiran; Olender, Thomas; Gingras-Gelinas, Philippe; Man-Kin Wong, Matthew; C.L. Robinson, Daniel; Bandukwala, Hina; G. Palii, Carmen; Neyret, Odile; Brand, Marjorie; Blais, Alexandre; Jeffrey Dilworth, F.

doi:10.1016/j.xpro.2021.100751

Public

Chromatin and transcription factor profiling in rare stem cell populations using CUT&Tag

Published in STAR Protocols • Aug 19, 2021

Authors:

Yuefeng Li

Kiran Nakka

Thomas Olender

Abstract

Muscle stem cells (MuSCs) are a rare stem cell population that provides myofibers with a remarkable capacity to regenerate after tissue injury. Here, we have adapted the Cleavage Under Target and Tagmentation technology to the mapping of the chromatin landscape and transcription factor binding in 50...

Subject

Stem cell

Biology

Transcription factor

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