Preclinical efficacy and clinical safety of clinical‐grade nebulized allogenic adipose mesenchymal stromal cells‐derived extracellular vesicles

Shi, Mengmeng; Yang, Qingyuan; Monsel, Antoine; Yan, Jiayang; Dai, Chengxiang; Zhao, Jingya; Shi, Guochao; Zhou, Min; Zhu, Xue‐mei; Li, Su‐ke; Li, Ping; Wang, Jing; Li, Meng; Lei, Ji‐gang; Xu, Dong; Zhu, Yinggang; Qu, Jieming

doi:10.1002/jev2.12134

Public

Preclinical efficacy and clinical safety of clinical‐grade nebulized allogenic adipose mesenchymal stromal cells‐derived extracellular vesicles

Published in Journal of Extracellular Vesicles • Aug 1, 2021

Authors:

Mengmeng Shi

Qingyuan Yang

Antoine Monsel

Abstract

Abstract Mesenchymal stromal cell‐derived extracellular vesicles (MSC‐EVs) turn out to be a promising source of cell‐free therapy. Here, we investigated the biodistribution and effect of nebulized human adipose‐derived MSC‐EVs (haMSC‐EVs) in the preclinical lung injury model and explored the safety ...

Subject

Mesenchymal stem cell

Medicine

Extracellular vesicle

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!