Quantification of polyreactive immunoglobulin G facilitates the diagnosis of autoimmune hepatitis

Taubert, Richard; Engel, Bastian; Diestelhorst, Jana; Luise Hupa‐Breier, Katharina; Behrendt, Patrick; Baerlecken, Niklas; Sühs, Kurt‐Wolfram; K. Janik, Maciej; Zachou, Kalliopi; Sebode, Marcial; Schramm, Christoph; Londoño, María‐Carlota; Habès, Sarah; Htun Oo, Ye; Lalanne, Claudine; Pape, Simon; Schubert, Maren; Hust, Michael; Dübel, Stefan; Thevis, Mario; Jonigk, Danny; Beimdiek, Julia; F. R. Buettner, Falk; P.H. Drenth, Joost; Muratori, Luigi; Adams, David; Dyson, Jessica; Renand, Amédée; Graupera, Isabel; W. Lohse, Ansgar; Ν. Dalekos, George; Milkiewicz, Piotr; Stangel, Martin; Maasoumy, Benjamin; Witte, Torsten; Wedemeyer, Heiner; P. Manns, Michael; Jaeckel, Elmar

doi:10.1002/hep.32134

Public

Quantification of polyreactive immunoglobulin G facilitates the diagnosis of autoimmune hepatitis

Published in Hepatology • Sep 2, 2021

Authors:

Richard Taubert

Bastian Engel

Jana Diestelhorst

Abstract

BACKGROUND AND AIMS: Detection of autoantibodies is a mainstay of diagnosing autoimmune hepatitis (AIH). However, conventional autoantibodies for the workup of AIH lack either sensitivity or specificity, leading to substantial diagnostic uncertainty. We aimed to identify more accurate serological ma...

Subject

Autoimmune hepatitis

Autoantibody

Medicine

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