Effect of Salt Substitution on Cardiovascular Events and Death

Neal, Bruce; Wu, Yangfeng; Feng, Xiangxian; Zhang, Ruijuan; Zhang, Yuhong; Shi, Jingpu; Zhang, Jianxin; Tian, Maoyi; Huang, Liping; Li, Zhifang; Yu, Yan; Zhao, Yi; Zhou, Bo; Sun, Jixin; Liu, Yishu; Yin, Xuejun; Hao, Zhixin; Yu, Jie; Li, Ka‐Chun; Zhang, Xinyi; Duan, Peifen; Wang, Faxuan; Ma, Bing; Shi, Weiwei; Luca Di Tanna, Gian; Stepien, Sandrine; Shan, Sana; Pearson, Sallie‐Anne; Li, Nicole; L. Yan, Lijing; R. Labarthe, Darwin; Elliott, Paul

doi:10.1056/nejmoa2105675

Public

Effect of Salt Substitution on Cardiovascular Events and Death

Published in New England Journal of Medicine • Aug 29, 2021

Authors:

Bruce Neal

Yangfeng Wu

Xiangxian Feng

Abstract

BACKGROUND: Salt substitutes with reduced sodium levels and increased potassium levels have been shown to lower blood pressure, but their effects on cardiovascular and safety outcomes are uncertain. METHODS: We conducted an open-label, cluster-randomized trial involving persons from 600 villages in ...

Subject

Blood pressure

Potassium

Salt (chemistry)

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