Critical Period After Stroke Study (CPASS): A phase II clinical trial testing an optimal time for motor recovery after stroke in humans

W. Dromerick, Alexander; Geed, Shashwati; Barth, Jessica; Brady, Kathaleen; L. Giannetti, Margot; Mitchell, Abigail; A. Edwardson, Matthew; Tan, Ming; Zhou, Yizhao; L. Newport, Elissa; Farrar Edwards, Dorothy

doi:10.1073/pnas.2026676118

Public

Critical Period After Stroke Study (CPASS): A phase II clinical trial testing an optimal time for motor recovery after stroke in humans

Published in Proceedings of the National Academy of Sciences • Sep 20, 2021

Authors:

Alexander W. Dromerick

Shashwati Geed

Jessica Barth

Abstract

Significance Restoration of postinjury brain function is a signal neuroscience challenge. Animal models of stroke recovery demonstrate time-limited windows of heightened motor recovery, similar to developmental neuroplasticity. However, no equivalent windows have been demonstrated in humans. We repo...

Subject

Stroke (engine)

Stroke recovery

Physical medicine and rehabilitation

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