Formation of a protein corona on the surface of extracellular vesicles in blood plasma

Á. Tóth, Eszter; Turiák, Lilla; Visnovitz, Tamás; Cserép, Csaba; Mázló, Anett; W. Sódar, Barbara; Försönits, András; Petővári, Gábor; Sebestyén, Anna; István Komlósi, Zsolt; Drahos, László; Kittel, Ágnes; Nagy, György; Bácsi, Attila; Dénes, Ádám; Song Gho, Yong; Szabó-Taylor, Katalin; I. Buzás, Edit

doi:10.1002/jev2.12140

Public

Formation of a protein corona on the surface of extracellular vesicles in blood plasma

Published in Journal of Extracellular Vesicles • Sep 1, 2021

Authors:

Eszter Á. Tóth

Lilla Turiák

Tamás Visnovitz

Abstract

In this study we tested whether a protein corona is formed around extracellular vesicles (EVs) in blood plasma. We isolated medium-sized nascent EVs of THP1 cells as well as of Optiprep-purified platelets, and incubated them in EV-depleted blood plasma from healthy subjects and from patients with rh...

Subject

Chemistry

Blood proteins

Differential centrifugation

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